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Title:
COMPOSITION AGAINST INFECTION WITH ROTAVIRUS AND PROCESS FOR PRODUCING THE SAME
Document Type and Number:
Japanese Patent JP2012012391
Kind Code:
A
Abstract:

To provide a composition having rotavirus infection preventing action.

The composition against infection with rotavirus is a microfiltration retentate of whey, a product obtained by treating whey using centrifugation and/or ammonium sulfate precipitation, or a dehydrated product thereof. The micropore diameter of a microfiltration membrane ranges from 0.004 to 1.4 μm. The centrifugal force in centrifugation ranges from 300 to 30,000 g. The saturation level in ammonium sulfate precipitation ranges from 30 to 100%. The whey is centrifuged/purified and adjusted to approximately neutral pH (6.8-7.2), and then, treated with the microfiltration membrane. Further, after a process, wherein water is added to the retentate and then the retentate is subjected to microfiltration treatment, is repeated several times (usually three times), the retentate is dehydrated by a conventional method.


Inventors:
KANAMARU YOSHIAKI
NAKAMURA YOSHITAKA
TAKAHASHI TAKESHI
NAGABUCHI MASAYA
YAMAGUCHI MAKOTO
OTOMO HIDEO
NAKAZAWA KENICHI
Application Number:
JP2011134714A
Publication Date:
January 19, 2012
Filing Date:
June 17, 2011
Export Citation:
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Assignee:
MEIJI CO LTD
International Classes:
A61K35/20; A23C21/00; A23K1/16; A23K10/28; A23L1/30; A23L1/305; A61K38/00; A61P31/12; A61P31/14
Domestic Patent References:
JPH08116875A1996-05-14
JP2002255824A2002-09-11
JP2000300183A2000-10-31
JPH11512746A1999-11-02
JPH10501698A1998-02-17
JPH09509320A1997-09-22
JPH06189679A1994-07-12
JPH05244875A1993-09-24
JPH05236883A1993-09-17
JPH05269353A1993-10-19
JPH0899896A1996-04-16
JPH03218318A1991-09-25
JPS63133941A1988-06-06
JPS63135336A1988-06-07
Other References:
金丸義敬他: "ヒトロタウィルス感染を強力に阻害する牛乳タンパク質", 日本農芸化学会2001年度大会講演要旨集, JPN6010024761, 5 March 2001 (2001-03-05), pages 28 - 1, ISSN: 0002543161
永井さやか他: "ヒトロタウイルス細胞レセプター成分と類似する牛乳タンパク質", 日本農芸化学会2003年度大会講演要旨集, JPN6010024763, 5 March 2003 (2003-03-05), pages 218 - 3, ISSN: 0002543162
金丸義敬他: "ヒトロタウイルスの複製を強力に阻害する牛乳の高分子量糖タンパク質フラクション", 日本農芸化学会誌, vol. 76, no. 4, JPN6010024765, 2002, pages 400 - 401, ISSN: 0002543163
J. GENERAL VIROLOGY, 1991, VOL.72, PP.2467-2474, JPN6013057800, ISSN: 0002686111
J. VIROLOGY, 1990, VOL.64, NO.10, PP.4830-4835, JPN6013057801, ISSN: 0002686112
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto



 
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