Title:
COMPOSITION CONTAINING ALPHA-MSH-ANTAGONIST DIPEPTIDE CONJUGATE
Document Type and Number:
Japanese Patent JP2010235608
Kind Code:
A
Abstract:
To provide a cosmetic or pharmaceutical composition comprising dipeptide conjugates and an additive for oral or local administration.
The invention relates to a dipeptide conjugate having general formula, A-AA2-AA1-NH2 in the form of enantiomers or diastereoisomers and mixtures thereof including racemic mixtures. In the formula, A is a group corresponding to a monocarboxylic acid with general formula, HOOC-R, wherein R is a 1-24C linear or branched aliphatic group which can comprise one or more unsaturations, and/or which can comprise a phenyl group, or lipoic acid or the reduced form thereof, dihydrolipoic acid or N-lipoyllysine; and AA1 and AA2 are identical or different amino acids, and at least one of them is Lys (Lysine).
Inventors:
PINEL ANNE-MARIE
VERDIE PASCAL
DUBS PASCALINE
MARTINEZ JEAN
SUBRA GILLES
VERDIE PASCAL
DUBS PASCALINE
MARTINEZ JEAN
SUBRA GILLES
Application Number:
JP2010092089A
Publication Date:
October 21, 2010
Filing Date:
April 13, 2010
Export Citation:
Assignee:
CENTRE NAT RECH SCIENT
INST EUROPEEN BIOLOG CELLULAIR
UNIV DE MONTPELLIER 1
UNIV MONTPELLIER 2
INST EUROPEEN BIOLOG CELLULAIR
UNIV DE MONTPELLIER 1
UNIV MONTPELLIER 2
International Classes:
A61K38/00; A23L1/305; A61K8/64; A61K38/05; A61P3/04; A61P25/00; A61P25/18; A61P35/00; A61P37/02; A61P43/00; A61Q19/00; A61Q19/02; A61Q19/08; C07K5/04; C07K5/06; C07K5/065; C07K5/072; C07K5/09; C07K7/06; C07K14/685
Domestic Patent References:
| JP2003238387A | 2003-08-27 | |||
| JP2000512613A | 2000-09-26 | |||
| JP2003221311A | 2003-08-05 | |||
| JP2003238387A | 2003-08-27 | |||
| JP2000512613A | 2000-09-26 | |||
| JP2003221311A | 2003-08-05 |
Foreign References:
| WO2000064926A1 | 2000-11-02 | |||
| WO2000064926A1 | 2000-11-02 |
Other References:
JPN6010041461, ＱＵＩＬＬＡＮ， Ｊ．Ｍ． ｅｔ ａｌ．, "”Ｓｔｒｕｃｔｕｒｅ−ｂａｓｅｄ ｓｅａｒｃｈ ｆｏｒ ｐｅｐｔｉｄｅ ｌｉｇａｎｄｓ ｔｈａｔ ｃｒｏｓｓ−ｒｅａｃｔ ｗｉｔｈ ｍｅｌａｎｏｃｏｒｔｉｎ ｒｅｃｅｐｔｏｒｓ．”", ＰＨＡＲＭ． ＲＥＳ．, 199611, Ｖｏｌ．１３， Ｎｏ．１１, Ｐ．１６２４−１６３０
JPN6010041462, ＱＵＩＬＬＡＮ， Ｊ．Ｍ． ｅｔ ａｌ．, "”Ｃｏｍｂｉｎａｔｏｒｉａｌ ｄｉｆｆｕｓｉｏｎ ａｓｓａｙ ｕｓｅｄ ｔｏ ｉｄｅｎｔｉｆｙ ｔｏｐｉｃａｌｌｙ ａｃｔｉｖｅ ｍｅｌａｎｏｃｙｔｅ−ｓｔｉｍｕｌａｔｉｎｇ ｈｏｒｍｏｎｅ ｒｅｃｅ", ＰＲＯＣ． ＮＡＴＬ． ＡＣＡＤ． ＳＣＩ． ＵＳＡ, 19950328, Ｖｏｌ．９２， Ｎｏ．７, Ｐ．２８９４−２８９８
JPN6010041462, ＱＵＩＬＬＡＮ， Ｊ．Ｍ． ｅｔ ａｌ．, "”Ｃｏｍｂｉｎａｔｏｒｉａｌ ｄｉｆｆｕｓｉｏｎ ａｓｓａｙ ｕｓｅｄ ｔｏ ｉｄｅｎｔｉｆｙ ｔｏｐｉｃａｌｌｙ ａｃｔｉｖｅ ｍｅｌａｎｏｃｙｔｅ−ｓｔｉｍｕｌａｔｉｎｇ ｈｏｒｍｏｎｅ ｒｅｃｅ", ＰＲＯＣ． ＮＡＴＬ． ＡＣＡＤ． ＳＣＩ． ＵＳＡ, 19950328, Ｖｏｌ．９２， Ｎｏ．７, Ｐ．２８９４−２８９８
Attorney, Agent or Firm:
Keiichi Ota