Title:
ナノ粒子状ナプロキセンおよび制御放出ヒドロコドンを含む組成物
Document Type and Number:
Japanese Patent JP2009541359
Kind Code:
A
Abstract:
The invention relates to a compositions comprising a nanoparticulate naproxen composition in combination with a multiparticulate modified release hydrocodone composition that, upon administration to a patient, delivers a hydrocodone in a bimodal or multimodal manner. The multiparticulate modified release composition comprises a first component and at least one subsequent component; the first component comprising a first population of hydrocodone - comprising particles and the at least one subsequent component comprising a second population of hydrocodone-comprising particles, wherein the combination of the components exhibit a bimodal or multimodal release profile. The invention also relates to a solid oral dosage form comprising such a combination composition.
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Inventors:
Stark, paul
Divane, john
Fanning, niar
Gary
Jenkins, scott
Thing-Reki, Garbinder
Divane, john
Fanning, niar
Gary
Jenkins, scott
Thing-Reki, Garbinder
Application Number:
JP2009516756A
Publication Date:
November 26, 2009
Filing Date:
June 25, 2007
Export Citation:
Assignee:
Elan Pharma International Limited
International Classes:
A61K31/485; A61K9/06; A61K9/10; A61K9/12; A61K9/26; A61K9/48; A61K9/50; A61K9/54; A61K31/192; A61K47/02; A61K47/10; A61K47/12; A61K47/14; A61K47/16; A61K47/18; A61K47/20; A61K47/22; A61K47/24; A61K47/26; A61K47/28; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61K47/46; A61P11/14; A61P19/02; A61P29/00; A61P43/00
Foreign References:
| US20050031691A1 | 2005-02-10 | |||
| US20030129237A1 | 2003-07-10 | |||
| US6165506A | 2000-12-26 |
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri