Title:
ABH抗原を利用した炎症疾患改善用組成物
Document Type and Number:
Japanese Patent JP2012514634
Kind Code:
A
Abstract:
The present invention relates to a composition for improving inflammatory disease, and more specifically to a composition for improving inflammatory disease able to improve inflammatory reactions and the barrier function of epithelial tissue such as the skin, to enhance aging resistance and skin elasticity and to prevent or treat aging. The present invention makes it possible to control inflammatory reactions by modulating the expression and modulating the activity of ABH antigens, and thus the composition of the present invention can be employed as a development marker for therapeutic agents designed to soothe or treat or help in the treatment of disease caused by inflammatory reaction in body tissue and notably the skin expressed by ABH antigens, and can be used in the development of external preparations and cosmetics containing external preparations designed for the purposes such as restoration of normal function and moisturization, wrinkle enhancement, whitening and elasticity recovery in skin through modulation of differentiation of keratinocytes and the skin barrier function.
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Inventors:
Oh junhi
Jeong Ji Young
Lee Dong Hoon
Lee Sera
Kim Yong-cheon
Shin Jung Eun
Lee Jun Hyung Kyung
Jeong Jin Ho
Jeong Ji Young
Lee Dong Hoon
Lee Sera
Kim Yong-cheon
Shin Jung Eun
Lee Jun Hyung Kyung
Jeong Jin Ho
Application Number:
JP2011545293A
Publication Date:
June 28, 2012
Filing Date:
January 07, 2010
Export Citation:
Assignee:
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
International Classes:
A61K45/00; A61K8/60; A61K8/97; A61K31/7088; A61K36/07; A61K36/18; A61K36/25; A61K36/28; A61K36/53; A61K48/00; A61P1/04; A61P13/00; A61P17/00; A61P17/06; A61P17/10; A61P27/02; A61P29/00; A61P37/00; A61Q19/00
Domestic Patent References:
| JPS59216821A | 1984-12-06 | |||
| JP2008506508A | 2008-03-06 | |||
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Foreign References:
| WO2007061912A2 | 2007-05-31 | |||
| WO2007041327A1 | 2007-04-12 | |||
| WO2008147111A2 | 2008-12-04 |
Other References:
JPN6013035350; ＢＲＯＷＮ，Ｓ．Ｊ． ｅｔ ａｌ: Ｉｎｆｌａｍｍ Ｂｏｗｅｌ Ｄｉｓ Ｖｏｌ．１０， Ｎｏ．５, 2004, ｐ．５４６-５５６
Attorney, Agent or Firm:
Tamura
Junko Sugimura
Junko Sugimura