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Title:
COMPOSITION AND METHOD FOR INCREASING INSULIN SENSITIVITY
Document Type and Number:
Japanese Patent JP2014159482
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compositions and methods for increasing insulin sensitivity.SOLUTION: Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.

Inventors:
COWLEY MICHAEL A
MCKINNEY ANTHONY A
GARY TOLLEFSON
Application Number:
JP2014114552A
Publication Date:
September 04, 2014
Filing Date:
June 03, 2014
Export Citation:
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Assignee:
OREXIGEN THERAPEUTICS INC
International Classes:
A61K31/135; A61K31/485; A61K38/28; A61P3/10; A61P5/50; A61P43/00
Domestic Patent References:
JP2007536229A2007-12-13
JP2003520788A2003-07-08
JPS63284126A1988-11-21
JP2009516744A2009-04-23
JP2007536229A2007-12-13
JP2003520788A2003-07-08
JPS63284126A1988-11-21
Foreign References:
WO2004096201A12004-11-11
WO2004096201A12004-11-11
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro