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Title:
COMPOSITION AND METHOD FOR INCREASING TELOMERASE ACTIVITY
Document Type and Number:
Japanese Patent JP2014024861
Kind Code:
A
Abstract:

To provide methods and compositions for increasing telomerase activity in cells.

Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The method and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells.


Inventors:
Harley, Calvin B.
Chin, Allison C.
Akama, Tsutomu
IP, Nancy Yuk-yu
Wong, Yung-hou
Miller-martini, David M.
Application Number:
JP2013000219989
Publication Date:
February 06, 2014
Filing Date:
October 23, 2013
Export Citation:
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Assignee:
GERON CORP
International Classes:
A61K31/58; A23L1/30; A61K31/575; A61K31/70; A61K31/7048; A61K36/00; A61K36/48; A61P3/02; A61P3/10; A61P9/00; A61P9/10; A61P17/00; A61P17/02; A61P19/00; A61P19/02; A61P25/28; A61P31/18; A61P43/00; C07J1/00; C07J17/00; C12N5/071; C12Q1/02; C12N15/09; A61K; C07J
Domestic Patent References:
JP2011098991A2011-05-19
JP2002275086A2002-09-25
JPS6212791A1987-01-21
JP2001258505A2001-09-25
JPH07238026A1995-09-12
JP2002154979A2002-05-28
Foreign References:
Other References:
JPN6015009911; RUSSIAN CHEMIAL BULLETIN, INTERNATIONAL EDITION VOL.50, NO.6, 2001, P.1107-1112
JPN6015009912; KHIMIIA PRIRODNYKH SOEDINENII VOL.4, 1994, P.510-514
JPN7015002076; KHIMIIA PRIRODNYKH SOEDINENII 翻訳文 VOL.4, 1994, P.510-514
JPN6016010323; JOURNAL OF NATURAL PRODUCTS VOL.54, NO.3, 1991, P.810-815
JPN6016010326; J.NAT.PROD. VOL.61, 1998, P.1469-1472
Attorney, Agent or Firm:
山本 秀策
森下 夏樹