COMPOSITION AND METHOD FOR INCREASING TELOMERASE ACTIVITY

Japanese Patent JP2014024861

A

To provide methods and compositions for increasing telomerase activity in cells.

Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The method and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells.

HARLEY CALVIN B
CHIN ALLISON C
AKAMA TSUTOMU
IP NANCY YUK-YU
WONG YUNG-HOU
MILLER-MARTINI DAVID M

JP2013219989A

February 06, 2014

October 23, 2013

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GERON CORP

A61K31/58; A23L1/30; A23L33/00; A61K31/575; A61K31/70; A61K31/7048; A61K36/00; A61K36/48; A61P3/02; A61P3/10; A61P9/00; A61P9/10; A61P17/00; A61P17/02; A61P19/00; A61P19/02; A61P25/28; A61P31/18; A61P43/00; C07J1/00; C07J17/00; C12N5/071; C12Q1/02; C12N15/09; A61K; C07J

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Hidesaku Yamamoto
Natsuki Morishita

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