COMPOSITION AND METHOD FOR REDUCING RISK OF EPILEPTIC OCCURRENCE AND/OR FOR TREATMENT OF SEIZURE DISORDER

Title:

COMPOSITION AND METHOD FOR REDUCING RISK OF EPILEPTIC OCCURRENCE AND/OR FOR TREATMENT OF SEIZURE DISORDER

Document Type and Number:

Japanese Patent JP2011201910

Kind Code:

A

Abstract:

To provide the compounds useful for reducing the risk of epileptic occurrences and/or for alleviating epileptic phenomena in patients, and to provide the compositions including the compounds.

There are provided the compounds in which at least the following two components are chemically bonded, and compositions comprising the compounds: (a) vitamin B6-based component selected from pyridoxal, pyridoxamine, pyridoxine, their pharmaceutically acceptable functional derivatives and salts; and (b) at least one antiepileptic drug (AED) or anticonvulsive, neuroprotective drug or neurotropic compound or moiety. Further, epileptic episodes is prevented and alleviated by using the above compounds, and the side effects of antiepileptic drugs can be reduced.

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Inventors:

DOLINA SVETLANA
SHTEIMAN VITALY
VINNIKOVA MARINA
SHAPIRO ISRAEL

Application Number:

JP2011122141A

Publication Date:

October 13, 2011

Filing Date:

May 31, 2011

Export Citation:

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Assignee:

D-PHARM LTD
ADVANCED NEUROPROTECTIVE SYSTEMS LTD

International Classes:

C07D213/66; A61K31/44; A61K31/4415; A61K31/4439; A61K31/4709; A61K31/513; A61K31/515; A61P25/08; C07D213/02; C07D401/12; C07D403/12; A61K; C07D

Attorney, Agent or Firm:

Hideto Asamura
Hajime Asamura
Yuko Nagase
Yukihiro Ikeda

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