Title:
ヒト疾患処置用の新規糖薬剤の組成物
Document Type and Number:
Japanese Patent JP6415677
Kind Code:
B2
Abstract:
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases. In particular, compositions comprising a selectively depolymerized, branched galactoarabino-rhamnogalacturonate whose backbone is predominantly comprised of 1,4-linked galacturonic acid (GalA) moieties, with a lesser backbone composition of alternating 1,4-linked GalA and 1,2-linked rhamnose (Rha), which in-turn is linked to any number of side chains, including predominantly 1,4-b-D-galactose (Gal) and 1,5-a-L-arabinose (Ara) residues.
Inventors:
Elisa Somer
Peter G. Trevor
Anatole A. Krysov
Elena Czechova
Peter G. Trevor
Anatole A. Krysov
Elena Czechova
Application Number:
JP2017238700A
Publication Date:
October 31, 2018
Filing Date:
December 13, 2017
Export Citation:
Assignee:
GALECTIN THERAPEUTICS, INC.
International Classes:
A61K31/732; A61K31/145; A61K31/375; A61K31/704; A61K38/06; A61K45/00; A61P1/00; A61P1/16; A61P1/18; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P19/02; A61P27/02; A61P29/00; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP2011516543A | ||||
| JP2004535430A | ||||
| JP2002514663A |
Foreign References:
| US20080107622 | ||||
| US20050250735 | ||||
| US20060211653 |
Other References:
Carbohydrate Polymers,1987年,7,pp.143-158
Attorney, Agent or Firm:
Takuji Yamada
Michiko Matsutani
Sakurai Yoko
Michiko Matsutani
Sakurai Yoko