Title:
オキサゾリジノン抗菌薬の直腸送達のための組成物
Document Type and Number:
Japanese Patent JP2004520432
Kind Code:
A
Abstract:
There is provided a pharmaceutical composition suitable for rectal administration, the composition comprising at least one oxazolidinone antibacterial drug, for example linezolid, in a concentration effective for treatment and/or prophylaxis of a gram-positive bacterial infection, the at least one oxazolidinone being in particulate form having a particle size of about 0.5 mum to about 150 mum, dispersed in a carrier in which the oxazolidinone is poorly soluble. The composition is, for example, a suppository, an enema, a microenema or a rectal capsule.
Inventors:
Pena, Lorraine
McCurdy, Vincent Yee
Clark, Carol S
McCurdy, Vincent Yee
Clark, Carol S
Application Number:
JP2002571025A
Publication Date:
July 08, 2004
Filing Date:
February 05, 2002
Export Citation:
Assignee:
PHARMACIA & UPJOHN COMPANY
International Classes:
A61K9/00; A61K9/02; A61K9/14; A61K9/40; A61K31/195; A61K31/422; A61K31/5355; A61K31/5377; A61K31/541; A61K45/00; A61K47/14; A61K47/44; A61P31/04; (IPC1-7): A61K9/02; A61K9/14; A61K9/40; A61K31/5377; A61K31/541; A61K45/00; A61K47/14; A61K47/44; A61P31/04
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri