多能性幹細胞を除去するための組成物、及び多能性幹細胞の除去方法 - National University Corporation Hokkaido University

Title:

多能性幹細胞を除去するための組成物、及び多能性幹細胞の除去方法

Document Type and Number:

Japanese Patent JP7409670

Kind Code:

B2

Abstract:

An object is to provide a composition and a method for eliminating undifferentiated pluripotent stem cells remaining in a cell group induced to differentiate from pluripotent stem cells. It has been found that while dihydroorotate dehydrogenase inhibitors exhibit cytotoxic activity against pluripotent stem cells, they do not exhibit significant cytotoxic activity against differentiated cells such as somatic stem cells.

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Inventors:

Toru Kondo

Application Number:

JP2020561509A

Publication Date:

January 09, 2024

Filing Date:

December 19, 2019

Export Citation:

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Assignee:

National University Corporation Hokkaido University

International Classes:

C12N5/0735; C12N5/10; C12N9/02; C12N9/99

Domestic Patent References:

JP2018093823A
JP2018014972A
JP2017507649A
JP2014501518A
JP2010513362A

Foreign References:

US20150306080
WO2012057052A1

Other References:

Cell Chemical Biology,2018年06月21日,Vol.25,pp.705-717
Cell,2016年,Vol.167,pp.171-186

Attorney, Agent or Firm:

Patent Attorney Corporation St. Crest International Patent Office

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