Title:
疎水性生理活性物質を送達するための組成物および方法
Document Type and Number:
Japanese Patent JP6438406
Kind Code:
B2
Abstract:
Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In a more specific embodiment, the cationic delivery agent includes branched PEI. Methods of making the delivery composition, as well as kits and methods of use are also disclosed.
Inventors:
Ventura, Joseph
Shannon, Waddman
Slager, Joram
Magony Guru, Joseph Schmidt
Hagen Rosa, Robert W..
Shannon, Waddman
Slager, Joram
Magony Guru, Joseph Schmidt
Hagen Rosa, Robert W..
Application Number:
JP2015540868A
Publication Date:
December 12, 2018
Filing Date:
November 05, 2013
Export Citation:
Assignee:
Thermodix, Inc.
International Classes:
A61K47/34; A61K9/10; A61K31/337; A61P35/00
Domestic Patent References:
| JP2006500437A | ||||
| JP2006508912A |
Foreign References:
| WO2010111517A1 |
Other References:
BJU INTERNATIONAL,2008年,Vol.103,p.978-986
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto