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Title:
造血機能を提供するための組成物および方法
Document Type and Number:
Japanese Patent JP7041179
Kind Code:
B2
Abstract:
The present invention relates to methods and compositions for providing hematopoietic function to human patients in need thereof, by selecting a pool of expanded human cord blood stem/progenitor cell samples for administration to the patient, wherein the samples in the pool collectively do not mismatch the patient at more than 2 of the HLA antigens or alleles typed in the patient; and administering the selected pool of expanded human cord blood stem/progenitor cell samples to the patient. Methods for obtaining the pools of expanded human cord blood stem/progenitor cell samples, banks of frozen pools of expanded human umbilical cord blood stem/progenitor cell samples, and methods for producing such banks are also provided herein.

Inventors:
Bernstein, Irwin, Day.
Delaney, Colleen
Application Number:
JP2020020612A
Publication Date:
March 23, 2022
Filing Date:
February 10, 2020
Export Citation:
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Assignee:
Fred Hutchinson Cancer Research Center
International Classes:
A61K35/51; A61K35/14; A61K35/28; A61K35/50; A61P7/00; C07K16/28; C12N5/0789; G16B30/10
Domestic Patent References:
JP2005102656A
JP2008517948A
JP2006517975A
JP2008545755A
Foreign References:
US20040067583
Other References:
DELANEY COLLEEN,NOTCH-MEDIATED EXPANSION OF HUMAN CORD BLOOD PROGENITOR CELLS CAPABLE OF RAPID MYELOID RECONSTITUTION,NATURE MEDICINE,2010年02月,V16 N2,232(p.1-16)
VOLKER HUETTEN,TORSIONAL INTERHARMONIC INTERACTION 以下省略,PROCEEDINGS OF THE THIRTY-SEVENTH TURBO MACHINERY SYMPOSIUM 2008,2008年01月01日,P57-66
Curr Opin Immunol. 2006 Oct;18(5):571-5
Exp Hematol. 2005 Oct;33(10):1249-56.
Attorney, Agent or Firm:
Patent business corporation HARAKENZO WORLD PATENT & TRADEMARK