Title:
心不全を処置するための組成物および方法
Document Type and Number:
Japanese Patent JP4361800
Kind Code:
B2
Abstract:
Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
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Inventors:
Marrick, Faddy
Tomasi, Adam Lewis
Fen, bainian
Craneac, Erica Anne
Elias, Kathleen
Le Pupin
Smith, witney walter
Chan, Champin
Morgans, David Jay. Jr.
Tomasi, Adam Lewis
Fen, bainian
Craneac, Erica Anne
Elias, Kathleen
Le Pupin
Smith, witney walter
Chan, Champin
Morgans, David Jay. Jr.
Application Number:
JP2003559423A
Publication Date:
November 11, 2009
Filing Date:
December 20, 2002
Export Citation:
Assignee:
Site Kinetics, Incorporated
International Classes:
C07D213/64; C07D333/40; A61K31/381; A61K31/42; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4436; A61K31/4439; A61K31/444; A61K31/455; A61K31/497; A61P9/00; A61P9/04; C07D213/65; C07D213/75; C07D213/78; C07D213/80; C07D213/81; C07D261/18; C07D333/38; C07D401/04; C07D401/12; C07D401/14; C07D409/12; C07D413/12
Domestic Patent References:
| JP2005068160A | ||||
| JP9512528A | ||||
| JP49073492A | ||||
| JP58074665A | ||||
| JP48035117A | ||||
| JP11511442A |
Foreign References:
| US3577550 | ||||
| US3674850 | ||||
| WO2001005769A1 | ||||
| WO2000026191A1 |
Other References:
Kempter, Gerhard; Beerbalk, H. D.,Synthesis of potential plant protective agents and pesticides from substituted anilines,Wissenschaftliche Zeitschrift der Paedagogischen Hochschule Karl Liebknecht Potsdam,1983年,27(1),101-20
Tomita, Masao; Ikawa, Kenji,Syntheses of acid hydrazide derivatives containing the diphenyl ether nucleus. V. Cleavage of diphenyl ether derivatives by hydrazine hydrate. 3,Yakugaku Zasshi,1955年,75,457-60
Ivanov, A. V.; Kaminskii, A. Ya.; Gitis, S. S.; Kozina, Z. A.,Kinetics of the alkaline hydrolysis of meta- and ortho- substituted aryl ethers of 2,4-dinitrophenol,Reaktsionnaya Sposobnost Organicheskikh Soedinenii,1967年,4(2),290-301
White, G. A.; Thorn, G. D.,Thiophene carboxamide fungicides: structure-activity relationships with the succinate dehydrogenase complex from wild-type and carboxin-resistant mutant strains of Ustilago maydis,Pesticide Biochemistry and Physiology,1986年,25(2),188-204
Parlow, John J.; Mischke, Deborah A.; Woodard, Scott S.,Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides,Journal of Organic Chemistry ,1997年,62(17),5908-5919
Krogh, R.; Yunes, R. A.; Andricopulo, A. D.,Structure-activity relationships for the analgesic activity of gallic acid derivatives,Farmaco ,2000年,55(11-12),730-735
Tomita, Masao; Ikawa, Kenji,Syntheses of acid hydrazide derivatives containing the diphenyl ether nucleus. V. Cleavage of diphenyl ether derivatives by hydrazine hydrate. 3,Yakugaku Zasshi,1955年,75,457-60
Ivanov, A. V.; Kaminskii, A. Ya.; Gitis, S. S.; Kozina, Z. A.,Kinetics of the alkaline hydrolysis of meta- and ortho- substituted aryl ethers of 2,4-dinitrophenol,Reaktsionnaya Sposobnost Organicheskikh Soedinenii,1967年,4(2),290-301
White, G. A.; Thorn, G. D.,Thiophene carboxamide fungicides: structure-activity relationships with the succinate dehydrogenase complex from wild-type and carboxin-resistant mutant strains of Ustilago maydis,Pesticide Biochemistry and Physiology,1986年,25(2),188-204
Parlow, John J.; Mischke, Deborah A.; Woodard, Scott S.,Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides,Journal of Organic Chemistry ,1997年,62(17),5908-5919
Krogh, R.; Yunes, R. A.; Andricopulo, A. D.,Structure-activity relationships for the analgesic activity of gallic acid derivatives,Farmaco ,2000年,55(11-12),730-735
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita