Title:
エピゲノム編集のための組成物および方法
Document Type and Number:
Japanese Patent JP6929791
Kind Code:
B2
Abstract:
Disclosed herein are CRISPR/Cas9-based gene activation systems that include a fusion protein of a Cas9 protein and a protein having histone acetyltransferase activity, and methods of using said systems.
Inventors:
Gersbach Charles A
Hilton Isaac
Hilton Isaac
Application Number:
JP2017560481A
Publication Date:
September 01, 2021
Filing Date:
February 09, 2016
Export Citation:
Assignee:
DUKE UNIVERSITY
International Classes:
C07K19/00; C07K14/195; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09
Foreign References:
| WO2014197748A1 | ||||
| WO2014152432A1 |
Other References:
Nat. Biotechnol.,2015年 4月 6日,vol.33,p.510-519
Attorney, Agent or Firm:
Shinichiro Tanaka
Disciple Maru Ken
▲吉▼田 和彦
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Gen Tashiro
Disciple Maru Ken
▲吉▼田 和彦
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Gen Tashiro