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Title:
COMPOSITIONS AND METHODS FOR TREATING CROHN'S DISEASE AND RELATED CONDITIONS AND INFECTIONS
Document Type and Number:
Japanese Patent JP2021193154
Kind Code:
A
Abstract:
To provide compositions and methods for treating Crohn's disease and related conditions and infections.SOLUTION: The invention provides a "triple combination" therapy for treating, ameliorating and preventing Crohn's Disease (or Crohn syndrome, terminal or distal ileitis or regional enteritis) or related disorders and conditions in mammals, such as paratuberculosis in mammals, or Johne's disease, including genetically-predisposed and chronic disorders, where the microbial or bacterial flora of the bowel is at least one causative or symptom-producing factor; and compositions for practicing the same. In alternative embodiments, methods and compositions of the invention comprise or comprise uses of therapies, medications, formulations and pharmaceuticals comprising active agents that can suppress or eradicate the microbiota super-infection that causes Crohn's Disease or paratuberculosis infection in mammals.SELECTED DRAWING: None

Inventors:
GAURAV AGRAWAL
Application Number:
JP2021162697A
Publication Date:
December 23, 2021
Filing Date:
October 01, 2021
Export Citation:
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Assignee:
GAURAV AGRAWAL
International Classes:
A61K33/00; A61K9/06; A61K9/10; A61K9/20; A61K9/48; A61K31/198; A61K31/395; A61K31/407; A61K31/4164; A61K31/427; A61K31/43; A61K31/437; A61K31/438; A61K31/4409; A61K31/496; A61K31/4965; A61K31/498; A61K31/545; A61K31/555; A61K31/603; A61K31/606; A61K31/625; A61K31/65; A61K31/7016; A61K31/7048; A61K31/733; A61K35/74; A61K35/741; A61K35/745; A61K35/747; A61K36/28; A61K36/31; A61K36/48; A61K36/8962; A61K36/899; A61K36/8998; A61K38/43; A61K38/46; A61K38/47; A61K38/51; A61K39/395; A61K45/06; A61K47/02; A61K47/12; A61K47/18; A61K47/22; A61K47/26; A61K47/32; A61K47/36; A61K47/46; A61P1/04; A61P31/04; A61P43/00
Foreign References:
WO2007120720A22007-10-25
Other References:
MAYO. CLIN. PROC., vol. 75, JPN6017009080, 2000, pages 647 - 649, ISSN: 0005029164
JOURNAL OF CROHN'S AND COLITIS, vol. 4, JPN6017009081, 2010, pages 203 - 206, ISSN: 0005029165
ALIMENT. PHARMACOL. THER., vol. 20, JPN6017009082, 2004, pages 1329 - 1336, ISSN: 0005029166
DIGESTIVE DISEASES AND SCIENCES, vol. 35, no. 12, JPN6017009083, 1990, pages 1561 - 1565, ISSN: 0005029167
J. CLIN. GASTROENTEROL., vol. Vol.19(3), JPN6017009084, 1994, pages 202 - 205, ISSN: 0005029168
ROSSIGNOL MEDICAL GAS RESEARCH, vol. Vol.2(6), JPN6017009085, 2012, pages 1 - 11, ISSN: 0005029169
GUT PATHOGENS, vol. Vol.1(15), JPN6017009086, 2009, pages 1 - 6, ISSN: 0005029170
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto