Title:
眼障害の治療のための組成物および方法
Document Type and Number:
Japanese Patent JP5794721
Kind Code:
B2
Abstract:
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
Inventors:
Gadek, Thomas
Vernier, john
Vernier, john
Application Number:
JP2008512519A
Publication Date:
October 14, 2015
Filing Date:
May 17, 2006
Export Citation:
Assignee:
Sir Code Bioscience Incorporated
International Classes:
A61K31/198; A61K9/06; A61K9/08; A61K9/10; A61K9/107; A61K9/12; A61K9/127; A61K9/20; A61K31/352; A61K38/08; A61P27/02
Domestic Patent References:
| JP2002509881A |
Foreign References:
| WO2005042710A1 | ||||
| WO2005044817A1 |
Other References:
Experimental Eye Research,2004年,Vol.78,p.823-835
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita