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Title:
COMPOUND ACTIVE AT NEW SITE ON RECEPTOR-OPERATED CALCIUM CHANNEL USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDER AND DISEASE
Document Type and Number:
Japanese Patent JP2009143927
Kind Code:
A
Abstract:

To provide a compound useful for therapeutic treatment of a neurological disease or disorder such as stroke, head trauma, spinal cord injury, epilepsy, and anxiety, or a neurodegenerative disease such as Alzheimer's disease, Huntington's disease and Parkinson's disease, or useful for a muscle relaxant, an analgesic or an adjuvant to a general anesthetic.

An amine compound exemplified by a structure of the chemical formula of the figure is illustrated for example.


Inventors:
MUELLER ALAN L
VAN WAGENEN BRADFORD C
DELMAR ERIC G
BALANDRIN MANUEL F
MOE SCOTT T
ARTMAN LINDA D
BARMORE ROBERT M
Application Number:
JP2008331256A
Publication Date:
July 02, 2009
Filing Date:
December 25, 2008
Export Citation:
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Assignee:
NPS PHARMA INC
International Classes:
A61K31/405; C07C211/27; A61K31/135; A61K31/136; A61K31/137; A61K31/138; A61K31/14; A61K31/165; A61K31/17; A61K31/295; A61K31/381; A61K31/40; A61K31/403; A61K31/404; A61K31/4045; A61K31/4409; A61K31/4462; A61K31/4465; A61K45/00; A61P9/10; A61P9/12; A61P21/02; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/28; A61P43/00; C07C211/29; C07C217/60; C07C217/62; C07C233/22; C07C235/34; C07C237/22; C07C279/12; C07D209/18; G01N33/53; G01N33/566
Domestic Patent References:
JP2004002437A2004-01-08
JP2007314556A2007-12-06
Foreign References:
GB119835A1918-10-17
Attorney, Agent or Firm:
Reiko Tanaka
Koji Morita