COMPOUND EXHIBITING PGD2 RECEPTOR ANTAGONISM

Japanese Patent JP2010132680

A

To provide a new compound exhibiting CRTH2 receptor antagonism.

The compound is expressed by formula (I) [a group expressed by formula (A1) which is a part of the formula (I) is expressed by formula (A2); in the formulae, Z3expresses =N- or =C(-R7)-; R4, R5, R6and R7each independently expresses H, a halogen or the like; R1expresses carboxy, an alkyloxycarbonyl or the like; Z4expresses -N= or -C(-R2)=; R2expresses H, an alkyl or the like: R15expresses H or an alkyl].

COPYRIGHT: (C)2010,JPO&INPIT

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TANIMOTO NORIHIKO
HIRAMATSU YOSHIHARU
MITSUMORI SUSUMU
INAGAKI MASANAO

JP2010018499A

June 17, 2010

January 29, 2010

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SHIONOGI & CO

C07D209/14; A61K31/403; A61K31/405; A61K31/407; A61K31/437; A61K31/4375; A61K31/4439; A61K31/454; A61K31/4709; A61P9/00; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P25/00; A61P31/04; A61P33/02; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D209/58; C07D209/88; C07D401/04; C07D401/06; C07D403/04; C07D403/06; C07D409/12; C07D409/14; C07D471/04

JPH04257578A	1992-09-11
JPH04234846A	1992-08-24
JPH03151360A	1991-06-27
JP4484108B2	2010-06-16

Kenichi Sugita
Hiromitsu Takayama

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