COMPOUND FOR INFLAMMATION AND IMMUNE-RELATED USE

Title:

COMPOUND FOR INFLAMMATION AND IMMUNE-RELATED USE

Document Type and Number:

Japanese Patent JP2012176959

Kind Code:

A

Abstract:

To provide a compound useful for immunosuppression and/or to treat or prevent inflammatory conditions and immune disorders.

The invention relates to compounds of structural formulas (I), (VII) and (XI): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X₁, X₂, X₃, Y, Z, L, R₁, R₂, R₃, R₁₈ and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

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Inventors:

SUN LIJUN
CHEN SHOUJUN
XIA ZHI QIANG
JIANG JUN
XIE YU
ZHANG JUNYI

Application Number:

JP2012100291A

Publication Date:

September 13, 2012

Filing Date:

April 25, 2012

Export Citation:

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Assignee:

SYNTA PHARMACEUTICALS CORP

International Classes:

C07C233/81; A61K31/216; A61K31/40; A61K31/41; A61K31/415; A61K31/4196; A61K31/421; A61K31/4245; A61K31/426; A61K31/433; A61K31/44; A61K31/4406; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/5375; A61P37/06; A61P43/00; C07D207/335; C07D213/36; C07D213/55; C07D213/64; C07D213/79; C07D231/12; C07D249/08; C07D257/04; C07D263/32; C07D271/06; C07D277/28; C07D285/12; C07D285/135; C07D295/12; C07D401/12; C07D405/12; C07D409/12; C07D417/12

Domestic Patent References:

JP2005508357A

2005-03-31

Foreign References:

WO2005009539A2

2005-02-03

Attorney, Agent or Firm:

Masayuki Masabayashi

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