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Title:
COMPOUND AND METHOD FOR SYNTHESIZING SULFOINDOCYANINE DYE
Document Type and Number:
Japanese Patent JP2007016038
Kind Code:
A
Abstract:

To provide new intermediates having an indolenine nucleus which are useful in the synthesis of fluorescent sulfoindocyanine dyes.

New intermediates having an indolenine nucleus which are useful in the synthesis of fluorescent sulfoindocyanine dyes are disclosed. Dyes synthesized using such intermediates do not contain a reactive group which will covalently attach to a target molecule at an amine- or hydroxy-containing site. Rather, these intermediates are linked to an enzyme substrate or a member of a specific bonding pair. Also included are tyramide-containing sulfoindocyanine dyes.


Inventors:
BOBROW MARK NORMAN
ERICKSON THOMAS JOSEPH
Application Number:
JP2006221123A
Publication Date:
January 25, 2007
Filing Date:
August 14, 2006
Export Citation:
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Assignee:
NEN LIFE SCIENCE PROD INC
International Classes:
C07D209/08; C07D209/14; G01N33/533; C07D495/04; C09B23/00; C09B23/02; G01N21/78; G01N33/58
Domestic Patent References:
JPH06123740A1994-05-06
JP3863920B22006-12-27
Foreign References:
WO1996017628A11996-06-13
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Shishido Kaichi
Nobuo Ogawa