Title:
チャネル活性化プロテアーゼ阻害剤としての化合物および組成物
Document Type and Number:
Japanese Patent JP5270538
Kind Code:
B2
Abstract:
The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase,
Inventors:
David Sea Tully
Arnab Kay Chatterjee
Hank Michael James Petrossi
Buddhist Burslaya
Glen Spragon
Arnab Kay Chatterjee
Hank Michael James Petrossi
Buddhist Burslaya
Glen Spragon
Application Number:
JP2009512221A
Publication Date:
August 21, 2013
Filing Date:
May 15, 2007
Export Citation:
Assignee:
IRM,LLC
International Classes:
C07D413/12; C07D413/14; C07D417/12; C07D417/14; A61K31/424; A61K31/427; A61K31/428; A61K31/4439; A61K31/454; A61K31/5377; A61P11/00; A61P11/06; A61P29/00; A61P31/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2000256396A | ||||
| JP2002138048A | ||||
| JP2005060379A | ||||
| JP2000506838A | ||||
| JP2002535394A | ||||
| JP4297446A | ||||
| JP2004509085A |
Attorney, Agent or Firm:
Mitsuo Tanaka
Aoyama Aoi
Mitsutaka Iwasaki
Aoyama Aoi
Mitsutaka Iwasaki