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Title:
消化管障害を処置するために有用な化合物
Document Type and Number:
Japanese Patent JP7292207
Kind Code:
B2
Abstract:
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Inventors:
Dragori, Dean
Dotsenko, Irina
Lewis, Jason
Application Number:
JP2019537185A
Publication Date:
June 16, 2023
Filing Date:
January 09, 2018
Export Citation:
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Assignee:
Alderix, Incorporated
International Classes:
C07C311/29; A61K31/18; A61K31/40; A61K31/4015; A61K31/4439; A61K31/4462; A61K31/495; A61K31/496; A61K45/00; A61K47/55; A61P1/00; A61P1/04; A61P1/10; A61P1/12; A61P1/14; A61P1/16; A61P3/00; A61P3/02; A61P3/06; A61P3/10; A61P5/14; A61P7/00; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P17/00; A61P17/02; A61P17/14; A61P19/00; A61P19/02; A61P21/00; A61P25/00; A61P25/18; A61P25/20; A61P25/32; A61P29/00; A61P37/02; A61P37/08; A61P39/02; A61P43/00; C07D207/14; C07D207/273; C07D207/48; C07D211/56; C07D249/04; C07D295/096; C07D295/205; C07D401/12; C07D401/14; C07D403/14; C07D451/02; C07D471/08; C07D487/08
Domestic Patent References:
JP2016516779A
JP2015527355A
JP2012501303A
JP2012514009A
JP2005515205A
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto