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Title:
CRTH2及び/又はPGD2受容体調節物質としての化合物、並びにぜん息及びアレルギー性炎症を治療するためのその使用
Document Type and Number:
Japanese Patent JP5537417
Kind Code:
B2
Abstract:
Compounds, compositions and methods that are useful in the treatment of inflammatory and immune-related diseases and conditions are provided herein. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives.

Inventors:
Brown, machine
Ji Young-son, Michael Gee
Lee, Anne-Ron
Lieu, Jouen
Sara Lee
Medulla, Giulio Sea
Cien, Wan
One, Shimei
One, Intsuai
Application Number:
JP2010506316A
Publication Date:
July 02, 2014
Filing Date:
May 01, 2008
Export Citation:
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Assignee:
Amjien Incorporated
International Classes:
C07D209/08; A61K31/4035; A61K31/404; A61K31/416; A61K31/4184; A61K31/428; A61K31/437; A61K31/47; A61K31/4704; A61K31/573; A61K45/00; A61P1/04; A61P3/10; A61P7/02; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P25/00; A61P25/04; A61P27/02; A61P29/00; A61P29/02; A61P31/04; A61P31/12; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D209/10; C07D209/34; C07D209/42; C07D209/48; C07D215/38; C07D231/56; C07D235/08; C07D277/82; C07D471/04
Domestic Patent References:
JP2006516143A
JP2006507336A
JP2004531479A
JP2004517851A
JP2000026430A
JP2002506851A
JP2083376A
JP2001518508A
JP2049778A
JP2007504122A
Foreign References:
WO2005010202A1
Other References:
Gimisis, Thanasis; Koreeda, Masato,A highly efficient synthesis of 3-methylcholanthrene,Journal of Organic Chemistry,1993年,58(25),7158-61
Logemann, W.; Lauria, F.; Fachinelli, E.,Tuberculostatic activity of some polycyclic oxocarboxylic acids,Farmaco, Edizione Scientifica,1956年,11,274-85
Attorney, Agent or Firm:
Kayo Shiina
Kawaguchi International Patent Office
Katsuma Osaki
Chihiro Watanabe
Mitsuaki Tsubokura



 
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