Title:
ホスホジエステラーゼ４を阻害する化合物・製法及びその薬物用途
Document Type and Number:
Japanese Patent JP6885557
Kind Code:
B2
Abstract:
The disclosure relates to the field of medicinal chemistry, in particular, to a class of small molecule compounds for inhibiting phosphodiesterase 4 (I), a preparation method thereof and a pharmaceutical composition comprising the compound. The pharmacodynamic test proves that the compound of the disclosure has the inhibitory activity of PDE-4 enzyme and the efficacy of inflammation treatment.
Inventors:
What Hiroe
Akirakyo Profit
Xu Qin Dragon
Lee Feng
Liu Tamanaka
Kaoru Moga
Zhao Flame
Akirakyo Profit
Xu Qin Dragon
Lee Feng
Liu Tamanaka
Kaoru Moga
Zhao Flame
Application Number:
JP2020545430A
Publication Date:
June 16, 2021
Filing Date:
December 25, 2018
Export Citation:
Assignee:
合肥医工医葯股▲ふん▼有限公司
Hefei Onru Special Anther Industry Co., Ltd.
Hefei Onru Special Anther Industry Co., Ltd.
International Classes:
C07F5/02; A61K31/69; A61P29/00; A61P43/00
Foreign References:
| US20060234981 | ||||
| CN106831840A |
Attorney, Agent or Firm:
Kimura Mitsuru
Taiji Morikawa
Kei Sakurada
Mie Hideki
Taiji Morikawa
Kei Sakurada
Mie Hideki