Title:
細胞の検出のための化合物および方法
Document Type and Number:
Japanese Patent JP2010517939
Kind Code:
A
Abstract:
The invention relates to compounds comprising an ester group for the detection in vivo of cells undergoing cell death ("dying cells") such as, for example, cells undergoing apoptosis. These compounds are selectively retained in dying cells relative to normal cells. Thus, the compounds may be used in the detection, diagnosis and treatment of clinical conditions manifested by a cell death process.
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Inventors:
Jib, iran
Sylvan, Anat
Sylvan, Anat
Application Number:
JP2009544488A
Publication Date:
May 27, 2010
Filing Date:
January 03, 2008
Export Citation:
Assignee:
APOSENSE LTD.
International Classes:
C07C69/675; A61B5/055; A61K49/00; A61K49/04; A61K51/00; G01N33/60; G01T1/161
Domestic Patent References:
| JP2007523059A | 2007-08-16 | |||
| JPS5939849A | 1984-03-05 | |||
| JPS5939854A | 1984-03-05 |
Foreign References:
| US4578503A | 1986-03-25 | |||
| US20050158239A1 | 2005-07-21 |
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda
Miho Ikegami
Makoto Onda
Atsushi Honda
Miho Ikegami