Title:
リン酸輸送を阻害する化合物及び方法
Document Type and Number:
Japanese Patent JP5823514
Kind Code:
B2
Abstract:
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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Inventors:
Lewis, Jason, Gee.
Jacobs, Jeffrey, W.
Like, Nicholas
Reed Better, Michael, Earl.
Bell,noah
Chan, Han-Ting
Chen, Tao
Navel mark
Chamotte, Dominique
Carreras, Christopher
Ravent, eric
Jacobs, Jeffrey, W.
Like, Nicholas
Reed Better, Michael, Earl.
Bell,noah
Chan, Han-Ting
Chen, Tao
Navel mark
Chamotte, Dominique
Carreras, Christopher
Ravent, eric
Application Number:
JP2013518849A
Publication Date:
November 25, 2015
Filing Date:
July 07, 2011
Export Citation:
Assignee:
Arderix, Incorporated
International Classes:
C07D213/56; A61K31/4418; A61K31/4433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/505; A61K31/506; A61K31/5377; A61K31/541; A61K31/551; A61K31/59; A61K31/592; A61K31/593; A61K45/00; A61P3/00; A61P5/18; A61P7/08; A61P13/12; C07D213/68; C07D213/70; C07D213/74; C07D213/75; C07D213/81; C07D239/28; C07D239/34; C07D239/42; C07D401/04; C07D401/06; C07D401/10; C07D401/12; C07D405/12; C07D413/10; C07D417/12; C07D471/08
Domestic Patent References:
| JP2005514413A | ||||
| JP2003504403A | ||||
| JP2003531856A |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka