Title:
脂肪毒性損傷の低減のための化合物
Document Type and Number:
Japanese Patent JP7224331
Kind Code:
B2
Abstract:
Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein:or a pharmaceutically acceptable salt thereof.
Inventors:
Singh, Vijay Phi.
Anandang, Sampas-Kumah
Kevin Greenman
Kamal, Jishan
Anandang, Sampas-Kumah
Kevin Greenman
Kamal, Jishan
Application Number:
JP2020501125A
Publication Date:
February 17, 2023
Filing Date:
July 12, 2018
Export Citation:
Assignee:
Mayo Foundation for Medical Education and Research
International Classes:
C07D305/12; A61K31/365; A61P1/18; A61P3/04; A61P11/00; A61P13/12; A61P17/02; A61P17/10; A61P31/00; A61P31/04
Domestic Patent References:
| JP61152663A | ||||
| JP7070099A | ||||
| JP2007523131A |
Foreign References:
| US20150099800 | ||||
| US20120289588 | ||||
| WO2016102541A1 |
Other References:
Journal of the Chemical Society, Perkin Transactions 1,1998年,(8),P.1373-1382
Journal of Medicinal Chemistry,2008年,51(21),P.6970-6979
Journal of Medicinal Chemistry,2008年,51(21),P.6970-6979
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office
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