Title:
代謝病の治療用の化合物
Document Type and Number:
Japanese Patent JP2012503595
Kind Code:
A
Abstract:
There is provided novel compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type II diabetes, hypertension, ketoacidosis, obesity, glucose intolerance, and hypercholesterolemia and related disorders associated with abnormally high or low plasma lipoprotein, triglyceride or glucose levels.
Inventors:
Ulven, Tronde
Christiansen, Elisabeth
Christiansen, Elisabeth
Application Number:
JP2011520437A
Publication Date:
February 09, 2012
Filing Date:
July 23, 2009
Export Citation:
Assignee:
SYDDANSK UNIVERSITET
International Classes:
C07C57/42; A61K31/155; A61K31/192; A61K31/195; A61K31/20; A61K31/275; A61K31/381; A61K31/4192; A61K31/426; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4418; A61K31/47; A61P1/14; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P7/00; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P15/10; A61P17/00; A61P27/02; A61P35/00; A61P43/00; C07C27/02; C07C51/09; C07C57/60; C07C59/125; C07C59/48; C07C59/52; C07C59/68; C07C59/74; C07C59/76; C07C61/39; C07C201/12; C07C205/56; C07C227/18; C07C229/40; C07C253/30; C07C255/23; C07C255/57; C07C303/30; C07C309/73; C07D213/55; C07D213/61; C07D215/18; C07D249/06; C07D277/20; C07D277/30; C07D333/24
Foreign References:
| US20040192743A1 | 2004-09-30 | |||
| US20050131014A1 | 2005-06-16 | |||
| WO1999029640A2 | 1999-06-17 | |||
| WO2008071453A1 | 2008-06-19 | |||
| WO2002014262A1 | 2002-02-21 |
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda
Miho Ikegami
Makoto Onda
Atsushi Honda
Miho Ikegami