レチノイドX受容体に対する選択性を有する化合物

Title:

レチノイドX受容体に対する選択性を有する化合物

Document Type and Number:

Japanese Patent JP3727334

Kind Code:

B2

Abstract:

Compounds, compositions, and method for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.

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Inventors:

Behm, Marcus F
Hayman, Richard A.
The Rin

Application Number:

JP51870893A

Publication Date:

December 14, 2005

Filing Date:

April 22, 1993

Export Citation:

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Assignee:

Ligand Pharmaceuticals, Inc.

International Classes:

A01N53/00; A61K31/16; A61K31/165; A61K31/185; A61K31/19; A61K31/192; A61K31/235; A61K31/24; A61K31/336; A61K31/34; A61K31/341; A61K31/35; A61K31/352; A61K31/38; A61K31/381; A61K31/41; A61K31/435; A61K31/44; A61K31/4418; A61K31/443; A61K31/455; A61P5/00; A61P17/00; A61P35/00; A61P43/00; C07C57/26; C07C57/48; C07C57/50; C07C59/76; C07C63/36; C07C63/49; C07C63/66; C07C63/72; C07C63/74; C07C65/17; C07C65/19; C07C65/36; C07C65/38; C07C65/40; C07C69/76; C07C69/78; C07C233/66; C07C233/75; C07C233/81; C07C235/84; C07C257/00; C07C309/28; C07C327/16; C07C327/26; C07D207/40; C07D213/79; C07D213/80; C07D257/04; C07D303/02; C07D303/38; C07D307/34; C07D307/68; C07D311/58; C07D333/38; C07D333/40; C07D405/04; C07F9/58; C07C; (IPC1-7): C07C63/49; A61K31/165; A61K31/192; A61K31/235; A61K31/24; A61K31/336; A61K31/341; A61K31/352; A61K31/381; A61K31/41; A61K31/4418; A61K31/443; A61K31/455; A61P5/00; A61P17/00; A61P35/00; A61P43/00; C07C63/66; C07C63/74; C07C65/17; C07C65/19; C07C65/36; C07C65/40; C07C69/76; C07C233/66; C07C233/75; C07C233/81; C07C235/84; C07C309/28; C07C327/16; C07C327/26; C07D213/79; C07D213/80; C07D257/04; C07D303/02; C07D307/34; C07D311/58; C07D333/38; C07D333/40; C07D405/04

Domestic Patent References:

JP6330433A
JP63208541A
JP63243072A
JP8502238A

Attorney, Agent or Firm:

Aoyama Aoi
Kyousei Tamura
Minato Saito

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