Title:
糖尿病の治療又は予防用ジペプチジルペプチダーゼIV阻害剤としての縮合アミノピペリジン
Document Type and Number:
Japanese Patent JP5075125
Kind Code:
B2
Abstract:
The present invention is directed to novel substituted fused aminopiperidines which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Inventors:
Cocks, The Eason M
Scott Day, Edmondson
Masturbation, Anthony
Scott Day, Edmondson
Masturbation, Anthony
Application Number:
JP2008528132A
Publication Date:
November 14, 2012
Filing Date:
August 22, 2006
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D471/14; A61K31/155; A61K31/4375; A61P3/04; A61P3/06; A61P3/10; A61P43/00
Domestic Patent References:
| JP2008521813A | ||||
| JP2003300977A |
Foreign References:
| WO2003082817A1 | ||||
| WO2004018469A1 |
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama