Title:
CONDENSED HETEROCYCLIC DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM
Document Type and Number:
Japanese Patent JP2012167027
Kind Code:
A
Abstract:
To provide a novel compound having NPY Y5 receptor antagonism.
The compound is represented by formula (I) (wherein X is -SO2- or the like; Y1 is =C(-R8)- or the like; Y2 is -C(-R3)= or the like; Y3 is =C(-R1)- or the like; Z is -N= or the like; R1, R3, R8, R9, R11, and R12 are each hydrogen or the like; R2 is an optionally substituted alkyl group or the like; R4 is an optionally substituted aryl group or the like; R5 is an optionally substituted aryl group; and n is 1 or the like) and has been found to have NPY Y5 receptor antagonism.
Inventors:
HAYASHI KYOHEI
NISHIURA YUJI
WATANABE KANA
IKUMASA AKIRA
FUJIOKA MASAHIKO
TAMURA TOMOSUKE
TANAKA NOBUYUKI
OMORI NAOKI
NISHIURA YUJI
WATANABE KANA
IKUMASA AKIRA
FUJIOKA MASAHIKO
TAMURA TOMOSUKE
TANAKA NOBUYUKI
OMORI NAOKI
Application Number:
JP2011026694A
Publication Date:
September 06, 2012
Filing Date:
February 10, 2011
Export Citation:
Assignee:
SHIONOGI & CO
International Classes:
A61K31/4184; A61K31/422; A61K31/423; A61K31/427; A61K31/439; A61K31/4439; A61K31/454; A61K31/4709; A61K31/5355; A61P3/04; A61P43/00; C07D235/12; C07D235/14; C07D235/26; C07D235/28; C07D235/30; C07D263/58; C07D401/12; C07D401/14; C07D403/06; C07D403/12; C07D405/06; C07D405/12; C07D413/10; C07D413/12; C07D417/14; C07D453/02; C07D471/04; C07D235/10
Attorney, Agent or Firm:
Hiromitsu Takayama
Kenichi Sugita
Kenichi Sugita