縮合複素環誘導体およびその用途

Title:

縮合複素環誘導体およびその用途

Document Type and Number:

Japanese Patent JP5490030

Kind Code:

B2

Abstract:

The present invention provides a compound having a superior Smo inhibitory activity and lower toxicity, which is sufficiently satisfactory as a pharmaceutical product. The present invention provides a compound represented by the formula (I) wherein ring A is 5- to 7-membered ring optionally having substituent(s), where substituents are optionally bonded to each other to form a ring; X is O, S or NR1 (R1 is a hydrogen atom or a hydrocarbon group optionally having substituent(s)); R2 is carbamoyl optionally having substituent(s); and R3 is hydroxy optionally having substituent(s), or a salt thereof.

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Inventors:

Nobuhiro Fujii
Yuya Oguro
Satoshi Sasaki
Shigeru Kondo

Application Number:

JP2011022188A

Publication Date:

May 14, 2014

Filing Date:

February 03, 2011

Export Citation:

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Assignee:

Takeda GmbH

International Classes:

C07D471/04; A61K31/444; A61K31/4545; A61K31/4743; A61K31/4745; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/541; A61K31/55; A61K31/551; A61P35/00; A61P35/02; A61P35/04; C07D471/14; C07D495/04; C07D519/00

Domestic Patent References:

JP6184145A

Foreign References:

WO2008112913A1
WO2008110611A1
WO2007120827A1

Attorney, Agent or Firm:

Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki

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