CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED WITH TERTIARY HYDROXY GROUPS AS PI3K-γ INHIBITORS

Title:

CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED WITH TERTIARY HYDROXY GROUPS AS PI3K-γ INHIBITORS

Document Type and Number:

Japanese Patent JP2023085290

Kind Code:

A

Abstract:

To provide inhibitors of PI3K-γ which are useful for treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.SOLUTION: The invention provides compounds of Formula (I) in the figure or pharmaceutically acceptable salts thereof.SELECTED DRAWING: None

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Inventors:

BRENT DOUTY
ANDREW W BUESKING
DAVID M BURNS
ANDREW P COMBS
FALAHATPISHEH NIKOO
JALLURI RAVI KUMAR
DANIEL LEVY
PADMAJA POLAM
SHAO LIXIN
SHEPARD STACEY
ARTEM SHVARTSBART
SPARKS RICHARD B
YUE EDDY W

Application Number:

JP2023036727A

Publication Date:

June 20, 2023

Filing Date:

March 09, 2023

Export Citation:

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Assignee:

INCYTE CORP

International Classes:

C07D487/04; A61K31/4985; A61K31/506; A61K31/53; A61P1/04; A61P1/18; A61P7/00; A61P7/06; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/02; A61P11/06; A61P13/00; A61P13/08; A61P13/12; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D519/00

Attorney, Agent or Firm:

Michiko Matsutani
Yasushi Ochiai

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