縮合五環式ポリエーテル - University of North Carolina at Wilmington

Title:

縮合五環式ポリエーテル

Document Type and Number:

Japanese Patent JP4742040

Kind Code:

B2

Abstract:

Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds. wherein R, OR1, and R2 are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.

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Inventors:

Baden, Daniel, Gee.
Abraham, William, Em.
Bourg de Rice, Andrea, Jay.
Michele the Sophie

Application Number:

JP2006527065A

Publication Date:

August 10, 2011

Filing Date:

September 20, 2004

Export Citation:

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Assignee:

University of North Carolina at Wilmington

International Classes:

C07D493/22; A61K31/35; A61K31/353; A61K31/4184; A61K31/42; A61K31/4433; A61K31/506; A61K31/52; A61K31/661; A61K31/7072; A61P11/00; A61P11/06; A61P39/02; C07D493/04; C07D493/14; C07D519/00; C07H19/04

Other References:

LIU T-Z,TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS,2000年 7月21日,V56 N30,P5391-5404
WEGNER C D,CURRENT PHARMACEUTICAL DESIGN,NL,BENTHAM SCIENCE PUBLISHERS,2001年,V7 N3,P199-212

Attorney, Agent or Firm:

Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio

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