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Title:
NaPi−IIb阻害剤として有用な縮合チオフェン誘導体
Document Type and Number:
Japanese Patent JP6653410
Kind Code:
B2
Abstract:
The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular diease associated with chronic kidney disease.

Inventors:
David Andrew Coates
Kevin Robert Fails
Jeffrey Alan Peterson
Jeffrey Michael Skaryantz
Quan Long Shen
Matthew John Bali
John Laurie Wetello The Second
Dariush Stanislow Vodka
Yampin Shoe
Application Number:
JP2019527785A
Publication Date:
February 26, 2020
Filing Date:
August 08, 2017
Export Citation:
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Assignee:
Eli Lilly and Company
International Classes:
C07D409/12; A61K9/20; A61K31/496; A61K31/4995; A61K47/32; A61P3/00; A61P9/00; A61P13/12; C07D487/08
Domestic Patent References:
JP2013107880A
Foreign References:
WO2016026372A1
WO2014003153A1
WO2011136269A1
Attorney, Agent or Firm:
Norihito Yamao
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro