Title:
CONDENSED TRICYCLIC HETEROCYCLIC COMPOUND
Document Type and Number:
Japanese Patent JP2003104987
Kind Code:
A
Abstract:
To provide a new guanomine condensed tricyclic heterocyclic compound having antitumor activity.
The compound is expressed by formula (R1 is H or an alkyl; R2 is H, an alkyl, an alkenyl, an aryl, a heteroaryl, a cyclyl or a heterocyclyl; R3 and R4 are each independently H, an alkyl, an alkenyl, an aryl, a heteroaryl, a cyclyl, a heterocyclyl or (CRaRb)mX(CRcRd)nY; X is a bond, O, S or NRe; Y is an alkoxy, an aryloxy, a heteroaryloxy, OC(O)Re, C(O)Re, N(ReRe'), NReC(O)Re', S(O)2Re or SRe; (m) and (n) are each independently 1, 2, 3, 4 or 5; Ra, Rb, Rc, Rd, Re, and Re, are each independently H, an alkyl, an aryl, a heteroaryl, a cyclyl or a heterocyclyl; and R5 is H or a halogen).
Inventors:
LEE FANG YU
LEE FANG CHEN
YANG CHANG AN
YONG MA WEI
WU XU AI
YE WU QIU
HUA XIAO XU
LEE FANG CHEN
YANG CHANG AN
YONG MA WEI
WU XU AI
YE WU QIU
HUA XIAO XU
Application Number:
JP2002157957A
Publication Date:
April 09, 2003
Filing Date:
May 30, 2002
Export Citation:
Assignee:
YUNG SHIN PHARMACEUTICAL INDUS
International Classes:
A61K31/505; A61K31/519; A61P35/00; C07D487/14; (IPC1-7): C07D487/14; A61K31/519; A61P35/00
Attorney, Agent or Firm:
Hironobu Onda (1 person outside)
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