Title:
CCR5に対する抗体と抗膜融合ペプチドとの抱合体
Document Type and Number:
Japanese Patent JP2010500984
Kind Code:
A
Abstract:
The current invention is related to a conjugate comprising one or more antifusogenic peptides and an antibody against an HIV gp120 binding cell surface receptor, characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said antibody against an HIV gp120 binding cell surface receptor and to the pharmaceutical use of said conjugate.
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Inventors:
Brandt, Michael
Fisher, Stephan
Kopetsky, Erhard
Sankratri, Suryanarayana
Schumacher, Ralph
Fisher, Stephan
Kopetsky, Erhard
Sankratri, Suryanarayana
Schumacher, Ralph
Application Number:
JP2009524111A
Publication Date:
January 14, 2010
Filing Date:
August 14, 2007
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07K19/00; A61K39/395; A61P31/12; A61P31/18; C07K14/155; C07K16/28; C12P21/08
Foreign References:
| WO2001043779A2 | 2001-06-21 | |||
| WO2004108885A2 | 2004-12-16 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito