Title:
ビタミン関連物質の製造のための連続的光分解プロセス
Document Type and Number:
Japanese Patent JP2014500231
Kind Code:
A
Abstract:
The present application provides a novel method for generation of a vitamin D2 compound using a continuous flow photoisomerization reactor. A compound represented by formula I: [structure] as further defined herein, is mixed with a solvent and a sensitizer, and is then passed through the continuous flow photoisomerization reactor. If X3 and X4 of formula II is tert-butyldimethylsilyl, then formula II is mixed with a deprotection reagent to obtain the vitamin D2 analog.
Inventors:
Bauta william edward
Anderson Bruce Girard
Cantrell Jr. William Earl
Anderson Bruce Girard
Cantrell Jr. William Earl
Application Number:
JP2013528234A
Publication Date:
January 09, 2014
Filing Date:
September 01, 2011
Export Citation:
Assignee:
GENZYME CORPORATION
International Classes:
C07C401/00; A61P3/02; A61K31/592
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino