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Title:
CONTROLLED RELEASE AND DELIVERY OF PEPTIDE OR PROTEIN
Document Type and Number:
Japanese Patent JP2013189448
Kind Code:
A
Abstract:

To provide a method and composition for the controlled release of peptide or protein agent, and methods of manufacturing a composition and a device useful for the controlled release of the peptide or protein agents.

This invention relates to a composition for the controlled release of peptide or protein, having a biocompatible, bioerodible polymer wherein a glassy matrix phase containing the peptide or protein and a thermal protecting agent is dispersed. The glassy matrix phase has a glass transition temperature higher than the melt point of the polymer.


Inventors:
WANG YU-CHANG JOHN
YANG BING
JENNINGS ROBERT N JR
PROTTER ANDREW A
Application Number:
JP2013102933A
Publication Date:
September 26, 2013
Filing Date:
May 15, 2013
Export Citation:
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Assignee:
SCIOS INC
International Classes:
A61K38/00; A61K9/00; A61K9/16; A61K9/19; A61K47/26; A61K47/34; A61L27/00; A61L31/00; A61P9/00; A61P17/02; C07K14/475; C07K17/08; A61K9/20
Domestic Patent References:
JPH05508640A1993-12-02
JPH02503315A1990-10-11
Foreign References:
WO1996003978A11996-02-15
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto