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Title:
制御放出ヒドロコドン処方
Document Type and Number:
Japanese Patent JP5834052
Kind Code:
B2
Abstract:
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C 12 /C max ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours.

Inventors:
Oshlack, Benjamin
Fan, fan
Tonelli, Alfred, Pea.
Masslink, John
Application Number:
JP2013168584A
Publication Date:
December 16, 2015
Filing Date:
August 14, 2013
Export Citation:
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Assignee:
Euro-Certique S.A.
International Classes:
A61K9/14; A61K31/485; A61K9/16; C07D489/02; A61K9/20; A61K9/22; A61K9/26; A61K9/28; A61K9/48; A61K9/52; A61K47/14; A61K47/32; A61K47/38; A61P25/02; A61P25/04
Domestic Patent References:
JP6507645A
JP10508608A
JP7145056A
JP63030427A
JP5201856A
JP6056651A
Foreign References:
WO1998041194A1
WO1996008253A1
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki