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Title:
Controlled release and a method for the same of the ear sensory cell modulator constituent for the disposal of the obstacle of an ear
Document Type and Number:
Japanese Patent JP6013736
Kind Code:
B2
Abstract:
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with auris sensory cell modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

Inventors:
Richer Jay
Bollas benedict
Tramel Andrew M.
Duron Sergio G.
Pue Fabrice
De La Marie Lewis A.
Yekian
Level curl
Schaeff Michael Christopher
Harris Jeffrey Pee.
Application Number:
JP2011542272A
Publication Date:
October 25, 2016
Filing Date:
December 10, 2009
Export Citation:
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Assignee:
Otonomi, ink.
The Regents of The University of California
International Classes:
A61K31/13; A61K9/06; A61K31/155; A61K31/198; A61K31/381; A61K31/428; A61K31/445; A61K31/4453; A61K31/451; A61K31/453; A61K31/4535; A61K31/498; A61K31/513; A61K31/517; A61K31/55; A61K31/662; A61K47/34; A61P27/16; A61P43/00
Domestic Patent References:
JP2006502158A
Foreign References:
WO2007038949A1
WO2007119098A2
Other References:
LEE,S.H. et al.,Regional delivery of vancomycin using pluronic F-127 to inhibit methicillin resistant Staphylococcus,Journal of Controlled Release,2004年,Vol.96,No.1,p.1-7
Attorney, Agent or Firm:
Kazuhiro Kiyohara