CORTICOSTEROID DERIVATIVES

Title:

CORTICOSTEROID DERIVATIVES

Document Type and Number:

Japanese Patent JPS5955900

Kind Code:

A

Abstract:

21-Hydroxycorticosteroid esters which can have good solution stability and are therefore suitable for formulation into aqueous compositions for injection or infusion, have the formula St-O-CO-Y-(CH2)n-NR1R2 wherein St is the corticosteroid without its 21-hydroxy group; Y is a bond, -O- or -S-; n is an integer of from 4 to 9; and either R1 and R2 are each C1-4 alkyl optionally substituted by one hydroxyl group or -NR1R2 is a monocyclic heterocyclic group; or a salt thereof.

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Inventors:

BUREDORII DEIRU ANDAASON
ROBAATO AREN KONRADEI

Application Number:

JP15041183A

Publication Date:

March 31, 1984

Filing Date:

August 19, 1983

Export Citation:

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Assignee:

UPJOHN CO

International Classes:

A61K31/57; A61P9/00; A61P29/00; C07J41/00; C07J43/00; (IPC1-7): A61K31/57; C07J41/00

Attorney, Agent or Firm:

Yataro Sasai

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