Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
CREAM PREPARATION CONTAINING STABLE KETOPROFEN
Document Type and Number:
Japanese Patent JPS62298526
Kind Code:
A
Abstract:

PURPOSE: To provide the titled cream preparation having excellent stability, etc., and stably containing ketoprofen which is a non-steroidal analgesic and anti-inflammatory agent having excellent analgesic and anti-inflammatory activities.

CONSTITUTION: The objective cream preparation contains 0.5W6(wt)% ketoprofen [2-(3-benzoylphenyl)propionic acid], 0.1W5%, preferably 0.5W1.5% hydrophilic polymer (e.g. carboxyvinyl polymer), 0.5W10%, preferably 3W6% nonionic surfactant (e.g. sorbitan fatty acid ester), 2W30%, preferably 10W20% fatty acid ester (e.g. isopropyl palmitate), 0.05W3%, preferably 0.5W1.5% pH-modifier and 65W85% water. The preparation has excellent physical stability, high transcutaneous absorbability and low skin irritation.


Inventors:
NAKAGAWA AKIRA
MIYATA SATORU
Application Number:
JP14089686A
Publication Date:
December 25, 1987
Filing Date:
June 16, 1986
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
HISAMITSU PHARMACEUTICAL CO
International Classes:
A61K9/06; A61K31/19; A61P25/04; A61P29/00; C07C59/84; (IPC1-7): A61K9/06; A61K31/19; C07C59/84
Domestic Patent References:
JPS5883622A1983-05-19
Attorney, Agent or Firm:
Norio Saeki