Title:
CRYSTALLINE ACID-ADDITION SALT OF CEFDINIR AND CEFDINIR PRODUCTION METHOD USING THE SAME
Document Type and Number:
Japanese Patent JP2008189688
Kind Code:
A
Abstract:
To provide a crystalline acid-addition salt from cefdinir; to provide a production method of the acid-addition salt; and to provide a cefdinir production method using the acid-addition salt.
High purity cefdinir can be produced by a method comprising a step of preparing a crystalline cefdinir salt by reacting a cefdinir intermediate with a mixture acid of formic acid-sulfuric acid or formic acid-methane sulfonic acid and a step of reacting the resultant crystalline salt with a base in a solvent.
Inventors:
GUWAN-SUN RII
CHANG YOUNG KIL
KIM HONG SEON
PARK CHUL-HYUN
PARK GHA-SEUNG
KIM CHEOL-KYUNG
CHANG YOUNG KIL
KIM HONG SEON
PARK CHUL-HYUN
PARK GHA-SEUNG
KIM CHEOL-KYUNG
Application Number:
JP2008099293A
Publication Date:
August 21, 2008
Filing Date:
April 07, 2008
Export Citation:
Assignee:
HANMI PHARM IND CO LTD
International Classes:
C07D501/22; C07B61/00; C07D501/00; C07D501/14
Domestic Patent References:
| JP2000502700A | 2000-03-07 | |||
| JP2000514833A | 2000-11-07 | |||
| JPS5989689A | 1984-05-23 | |||
| JPH02790A | 1990-01-05 | |||
| JPH01250384A | 1989-10-05 | |||
| JP2000514090A | 2000-10-24 |
Attorney, Agent or Firm:
Takehiko Suzue
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Tetsuya Kazama
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Tetsuya Kazama