Title:
カナグリフロジン半水和物結晶を得るための結晶化手順
Document Type and Number:
Japanese Patent JP6851379
Kind Code:
B2
Abstract:
The present invention relates to an improved crystallization procedure to obtain canagliflozin hemihydrate crystals having a narrow particle size distribution by removing a small part of the crystalline suspension in the crystallization vessel from said vessel and subjecting said part to particle size reduction of the formed crystals followed by heating and reintroducting said part of the crystalline suspension again in the crystallization vessel which is kept within a specific temperature range.
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Inventors:
Ruben, Decayer
Laps, Stin
Rammelou, Thomas Joachim Landwald
Weats, Cohen Johann Hermann
Laps, Stin
Rammelou, Thomas Joachim Landwald
Weats, Cohen Johann Hermann
Application Number:
JP2018532225A
Publication Date:
March 31, 2021
Filing Date:
December 20, 2016
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07H7/04; A61K31/7042; A61P3/10
Domestic Patent References:
| JP2012532845A |
Foreign References:
| WO2008069327A1 | ||||
| WO1999067236A1 | ||||
| WO2004064806A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Uetake Yukiko
Yasuhito Suzuki
Eiji Katayama
Junko Kobayashi
Norio Omori
Uetake Yukiko
Yasuhito Suzuki