Title:
ピラゾロ［３，４－ｄ］ピリミジンの結晶
Document Type and Number:
Japanese Patent JP7282787
Kind Code:
B2
Abstract:
An object of the invention is to provide a crystal of (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-N-(4-(2-(dimethylamino)-2-oxoethyl)-2,3-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3-carboxamide which is excellent in stability and preferable from the viewpoint of manufacturing and formulation. The present invention provides a crystal having an X-ray powder diffraction spectrum having characteristic peaks at diffraction angles (2θ ± 0.2°) of 6.0°, 7.7°, 8.9°, 10.6°, 12.1°, 13.1°, 14.0°, 14.7°, 15.5°, 15.8°, 16.8°, 17.7°, 18.1°, 18.4°, 19.4°, 23.4°, 24.1°, 24.7°, 25.1° and 25.7°.
Inventors:
Sei Shimamura
Hiromi Oshiumi
Hiromi Oshiumi
Application Number:
JP2020539525A
Publication Date:
May 29, 2023
Filing Date:
August 28, 2019
Export Citation:
Assignee:
Taiho Pharmaceutical Co., Ltd.
International Classes:
C07D487/04; A61K31/519; A61P35/00
Foreign References:
| WO2017038838A1 |
Other References:
芦澤 一英、他,医薬品の多形現象と晶析の科学,丸善プラネット株式会社,2002年09月20日,第305-317頁
松岡 正邦,結晶多形の基礎と応用,普及版 第1刷,株式会社 シーエムシー出版,2010年10月22日,第105~117頁、第181~191頁
松岡 正邦,結晶多形の基礎と応用,普及版 第1刷,株式会社 シーエムシー出版,2010年10月22日,第105~117頁、第181~191頁
Attorney, Agent or Firm:
Arga Patent Office
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