Title:
トロンボポエチン受容体アゴニスト作用を有する環状化合物
Document Type and Number:
Japanese Patent JP4145654
Kind Code:
B2
Abstract:
Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: X<1>-Y<1>-Z<1> wherein X<1> is optionally substituted aryl, optionally substituted heteroaryl or the like; Y<1> is -NRCO-(CH2)0-2- or the like (wherein R is hydrogen atom or the like); and Z<1> is a cyclic group fused the same or different two ring selected from optionally substituted carbocyclic group and optionally substituted heterocyclic group.
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Inventors:
Hiroshi Takemoto
Takayama Masaki
Yutaka Yoshida
Takayama Masaki
Yutaka Yoshida
Application Number:
JP2002559401A
Publication Date:
September 03, 2008
Filing Date:
January 25, 2002
Export Citation:
Assignee:
Shionogi Pharmaceutical Co., Ltd.
International Classes:
C07D277/20; A61K31/426; A61K31/427; A61K31/433; A61K31/4709; A61K31/506; A61P7/00; A61P7/04; A61P7/06; A61P43/00; C07D277/46; C07D417/10; C07D417/12
Domestic Patent References:
| JP10130147A | ||||
| JP5155871A | ||||
| JP10287634A | ||||
| JP2002532423A |
Foreign References:
| WO2000005233A1 | ||||
| WO1997032863A1 |
Attorney, Agent or Firm:
Hideaki Yamauchi
Kenichi Sugita
Kenichi Sugita