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Title:
六員環式基を有する環状ジアミン化合物
Document Type and Number:
Japanese Patent JP4235103
Kind Code:
B2
Abstract:
A cyclic diamine compound of formula (1):wherein A is a single bond or C=C; X and Y are individually CH or a nitrogen atom; m is 1 or 2; and n is a number of 1 to 5; an acid-addition salt thereof, or a hydrate thereof. The compound has excellent inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation.

Inventors:
Tatsuhiko Kodama
Masahiro Tamura
Toshiaki Oda
Yuko Yamazaki
Nishikawa Masahiro
Takeshi Toi
Yoshinori Kyotani
Application Number:
JP2003508916A
Publication Date:
March 11, 2009
Filing Date:
June 27, 2002
Export Citation:
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Assignee:
Kowa Co., Ltd.
International Classes:
C07D295/08; A61K31/495; A61K31/496; A61K31/506; A61K31/551; A61P9/10; A61P11/06; A61P19/02; A61P29/00; A61P37/08; A61P43/00; C07D213/38; C07D239/26; C07D243/08; C07D295/096; C07D401/12
Domestic Patent References:
JP2003064057A
JP9143075A
JP11092382A
JP9309877A
JP2001500142A
Foreign References:
WO2003002536A1
WO2003002554A1
WO1998007702A1
WO1998016497A1
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Asano Yasutaka
Hiromi Matoba
Masaki Murata
Hiroto Yamamoto