Title:
カリウムチャネル機能のシクロアルキル阻害薬
Document Type and Number:
Japanese Patent JP4598397
Kind Code:
B2
Abstract:
Novel cycloalkyl compounds useful as inhibitors of potassium channel function (especially inhibitors of the K v l subfamily of voltage gated K + channels, especially inhibitors K v 1.5 which has been linked to the ultra-rapidly activating delayed rectifier K + current I Kur ), methods of using such compounds in the prevention and treatment of arrhythmia and I Kur -associated conditions, and pharmaceutical compositions containing such compounds.
Inventors:
John Lloyd
Yoon Ti Jung
Heather Finley
Lin Yang
Michael f gross
Surge board-in
Yoon Ti Jung
Heather Finley
Lin Yang
Michael f gross
Surge board-in
Application Number:
JP2003563493A
Publication Date:
December 15, 2010
Filing Date:
January 31, 2003
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
ICAGEN, INC.
ICAGEN, INC.
International Classes:
C07D217/22; A61K45/06; C07C233/58; C07C233/59; C07C233/60; C07C233/65; C07C235/06; C07C235/34; C07C235/46; C07C235/60; C07C279/16; C07C279/24; C07C279/28; C07C307/02; C07C307/04; C07C307/08; C07C307/10; C07C311/16; C07C311/29; C07C311/55; C07C311/59; C07C311/64; C07C323/62; C07D213/40; C07D213/69; C07D213/82; C07D233/48; C07D233/54; C07D233/76; C07D235/14; C07D239/42; C07D239/94; C07D239/95; C07D241/06; C07D249/04; C07D251/44; C07D251/46; C07D261/08; C07D261/14; C07D271/06; C07D295/13; C07D295/185; C07D295/215; C07D295/26; C07D307/68; C07D309/04; C07D309/08; C07D333/20; C07D333/28; C07D333/38; C07D333/58; C07D333/62; C07D409/12; C07D413/12; C07D471/04; C07D487/04; C07D521/00; A61K31/472; A61P9/06; C07D235/10; A61K
Domestic Patent References:
| JP2001514163A | ||||
| JP8253448A | ||||
| JP11049743A | ||||
| JP2011551A | ||||
| JP58043919A |
Foreign References:
| WO2000025770A1 | ||||
| WO2001087866A1 | ||||
| WO2001097787A1 |
Other References:
Journal of Medicinal Chemistry,2000年 9月21日,43(19),3566-3572
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka