Title:
ガンマ-セクレターゼ阻害剤としてのシクロヘキシルスルホン
Document Type and Number:
Japanese Patent JP4653486
Kind Code:
B2
Abstract:
Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.
Inventors:
Cheer Cheer, Ian
Harrison, Tamothy
Keller, Sonia
Alain Jiyoung, Nadein
Owens, Andrew Pate
Duncan Edward, Chiyo
Thomson, Joan
Williams, Susanna
Harrison, Tamothy
Keller, Sonia
Alain Jiyoung, Nadein
Owens, Andrew Pate
Duncan Edward, Chiyo
Thomson, Joan
Williams, Susanna
Application Number:
JP2004540932A
Publication Date:
March 16, 2011
Filing Date:
September 25, 2003
Export Citation:
Assignee:
Merck Sharp End Dome Limited
International Classes:
C07C317/30; A61K31/10; A61K31/18; A61K31/22; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/41; A61K31/415; A61K31/4164; A61K31/4196; A61K31/421; A61K31/425; A61K31/44; A61K31/4402; A61K31/4436; A61K31/4439; A61K31/5375; A61K31/5377; A61P25/28; A61P43/00; C07C315/04; C07C317/32; C07C317/44; C07D213/70; C07D213/71; C07D213/74; C07D231/18; C07D233/42; C07D233/84; C07D249/12; C07D257/04; C07D261/10; C07D275/02; C07D275/03; C07D277/36; C07D295/08; C07D295/088; C07D307/64; C07D333/34; C07D409/12; C07D417/12
Domestic Patent References:
| JP2004533428A | ||||
| JP2005524625A | ||||
| JP2005504042A | ||||
| JP2003526603A | ||||
| JP9169713A |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura